这一季的故事发生在上一季的3年后。这一季里，托尼（卡洛斯·博纳德 Carlos Bernard 饰）和米歇尔（蕾可·艾尔丝沃斯 Reiko Aylesworth 饰）结婚了，并且成为了CTU的主管，而杰克（基弗·萨瑟兰 Kiefer Sutherland 饰）的女儿金姆也加入CTU成为了一 名情报分析员。剧情由一具被扔在洛杉矶卫生中心外并感染了致命病毒的尸体开始。一个墨西哥毒枭为了让美国政府释放自己的哥哥，以致命病毒为恐吓。杰克也因此又踏上了反恐调查之路。而这一季里面，杰克的调查并不顺利，为了打入毒贩内部，杰克不惜染上毒瘾，这导致他在调查中困难重重。而白宫方面，获得连任的鲍尔默总统（丹尼斯·海斯伯特 Dennis Haysbert 饰）康复后身边多出了一位私人医生女友，而总统的弟弟韦恩成为了他的得力助手，在连任压力面前，又要化解这场生化危机。总统还能像前几次那样给予杰克强有力的支持吗？

　　Aired on HBO from 22 June 2003 to 22 February 2004

　　各位女士、先生，请欢迎美国总统葛兰艾伦华肯！
　　他是众议院院长也是个死硬的保守派，当巴特勒总统为了女儿被绑架的事件忙得焦头烂额时，华肯暂代总统职位，白宫的幕僚人员则夹在新旧总统间左右为难。绑架危机的化解及巴特勒重回总统宝座，是【白宫风云】第五季两条引人入胜的故事主轴。饰演白宫发言人的艾莉詹尼，也因她在第五季的精湛表现而荣获艾美奖最佳女主角奖。第五季可说是情节高潮迭起，也包括副总统出人意料之外的阵前换将，最高法院的大法官任命风波，及多位幕僚前往迦萨走廊的一趟致命之旅。

　　乔伊（马特·理勃兰 Matt LeBlanc 饰）和瑞秋（詹妮弗·安妮斯顿 Jennifer Aniston 饰）的恋情维持不久就发现彼此不适应身体上的交往，决定只做朋友。迈克克服自身障碍的迈克终于向菲比（莉莎·库卓 Lisa Kudrow 饰）求婚，两人终成眷属。钱德勒（马修·派瑞 Matthew Perry 饰）和摩妮卡（柯特妮·考克斯 Courteney Cox 饰）的代孕母亲艾瑞卡生了一对龙凤胎，Jack和Erica。 瑞秋通过马克的介绍决定前往巴黎工作。朋友们为她举行了告别派对，除了罗斯（大卫·休默 David Schwimmer 饰）她轮流跟朋友们告别。而此时罗斯意识到自己仍然爱着瑞秋，两人重修旧好，瑞秋也放弃了巴黎的工作。经历了十年间风风雨雨，大家分别离开公寓，都留下自己的一把钥匙......

　　Former police detective Adrian Monk (Tony Shalhoub), whose photographic memory and amazing ability to piece together tiny clues made him a local legend, has suffered from intensified obsessive-compulsive disorder and a variety of phobias since the unsolved murder of his wife, Trudy, in 1997. Now on psychiatric leave from the San Francisco Police Department and working as a freelance detective/ consultant on difficult cases, Monk hopes to convince his former boss, Captain Leland Stottlemeyer (Ted Levine), to allow him to return to the force. Stottlemeyer, who wavered between admiration for Monk and annoyance at his eccentricities during the first season, is becoming more of a friend to Monk as the series develops, frequently calling him in to help, as much for Monk's benefit as for his own. However, he knows Monk's limitations as well as his strengths and may still harbor doubts about the wisdom of allowing Monk to carry a gun or subdue a perpetrator. Stottlemeyer's second-in-command, Lieutenant Randall Disher (Jason Gray-Stanford), also seems to be developing both admiration and compassion for the man he once labeled "the defective detective."
　　Despite flaws and inadequacies all around, the three are becoming an increasingly effective team, with additional help from Monk's personal assistant. From the double-episode pilot through the first half of season three, Monk was aided by his nurse, Sharona Fleming (Bitty Schram). But in the tenth episode of the third season, Sharona was replaced by a new assistant, Natalie Teeger (Traylor Howard). Like Sharona, a divorcee with a son named Benjy, Natalie is a single parent, a widow with a daughter named Julie (Emmy Clarke). Unlike Sharona, Natalie is not a nurse but a former bartender with a fresh perspective on "Mr. Monk," as she still addresses her new boss.

　　Jake Foley is a computer technician for the NSA who secretly longs for a chance to work on the field. Circumstance puts him in a top secret laboratory, in the middle of a shootout between security guards and a saboteur. During the battle, a vial containing an experimental serum explodes, covering Jake with shrapnel. But it turns out that the serum is actually nanomites, microscopic submachines that heal his injuries and alter his body. Upon discovering his new mind-boggling powers, Jake begins to operate at an atomic level, possessing superhuman strength, lightning-fast speed, heightened hearing, magnified vision and the ability to communicate telepathically with computers. The NSA soon realizes Jake is an untested asset and forms a Special Ops team with him at its core. As Jake finally realizes his dream of being of being a field operative, he must also contend with the return of would-be girlfriend Sarah Heywood, who is involved in a Congressional investigation which threatens to expose his operation.

　　从这一季开始更换了片尾曲，体现出超人的进一步成长，要处理更困难的局面、对付更黑暗的敌人。

　　《赌城风云》(Las Vegas)这部快节奏、刺激的剧集继续讲述拉斯维加斯的精英保安队如何维护这个欲望之都最大赌场的安全。爱德华(Edward Melvin Deline，詹姆斯-凯恩饰演)，是Montecito赌城保安队主管。丹尼(Danny McCoy，乔什-杜哈明饰演)是一名出生于拉斯维加斯的前美国海军，他也加入了精英保安队。他们两一起面对老千，意图偷窃大笔金钱的竞争赌场等。
　　丹尼和爱德华唯一的女儿德琳达(Delinda Deline，莫莉-西姆斯饰演)的感情，Montecito赌城更换新老板，赌城一次次被盗。都是故事发展的线索。

　　警察比克与队长大卫组成一个临时的侦察队，克劳德特誓要破坏他们。比克独自生活在治安混乱的地区，比克与队长一次次的联手打击了犯罪团伙，为该地区带来和平与稳定，也为他们将来的退休金加上一个大分。《盾牌》是一部近年少见的极具争议性的连续剧，它打破了传统警匪片套路，把一群警官与各种罪案作斗争的同时，也面临各种自身问题的困扰，一个个有着复杂性格的警察跃然于屏幕之上，彻底打破了“警察就是好人”这种简单的界定。

　　此剧残暴程度美剧史上都少有，《监狱风云》将观众带到Oswald劳教所中，那里的玻璃笼子中关着残暴至极的重刑犯。汤姆·方塔纳创作了这个复杂的故事——开始于Tobias Beecher进入这所监狱，并随着他在监狱的转变而展开——达到了莎士比亚悲剧级别的高度。

　　在英美非常流行的剧集之一，属于与Buffy同类型的魔届奇幻电视剧，同样也都是WB公司出品。三个魅力非凡的女巫在普通人生活面具下，运用超凡的法术对抗邪恶黑暗力量的故事。音乐剧情都可圈可点。

　　每一个人的成长经历往往是艰苦的，特别是当您面对死亡之时。
　　对于女主角George Lass，生活是乏味的，每日只是做着一些沉闷的工作，在家亦只能够感到少少的温暖，莫非这个便是命运？但世事往往会令人惊喜，George在她新上任的工作中遇到意外而身亡，随后更被选中成为在其它人临死时出现，把灵魂带走的死神 (Grim Reaper)。
　　从此，她便以一个全新的身份，与其它一同被选中的死神一起，执行这个非常刺激的任务。虽然死神的工作对George 而言很有新鲜感，但她却需要时间去适应这个全新的生活，以及习惯面对着弱小的生命死亡但却无能为力。

　　Millions of people speak to God. What if God spoke back? Life just got a hell of a lot more confusing for teenage Joan Girardi, who already deals with feeling out of place in her family : her police chief father, her somewhat overbearing mother, her geeky younger brother and former football star older brother, now paralyzed. They'd never believe her if she told them that God is talking to her. Does Joan have a higher purpose on earth, or are these strange conversations just in her head? Written by Ted Weiland

　　As the 8th season begins, nothing in the firm is as we remember. Bobby, Linsay, Rebecca and Lucy are all gone, leaving Ellenor, Eugene and Jimmy at the helm. Ellenor also hires an old friend, attorney Alan Shore, recently fired from his firm for embezzlement. Jimmy and and Eugene defend a woman who killed a drug dealer in her neighborhood in cold blood, desperate to stop him from selling drugs to children. Ellenor and Jaimie defend a man accused of killing his wife and unborn child, but begin to suspect he is actually protecting the real killer.